Israa H Al-Ani
Al-Ahliyya Amman University, Jordan
Title: Formulation of levofloxacin as orodispersible tablets using readymade excipients blend in comparison to classic formulation strategies
Biography
Biography: Israa H Al-Ani
Abstract
Readymade excipients blends are gaining wide attention in pharmaceutical industry these days especially for tablet production. An orodispersible tablet is intended to be placed in the mouth where it disperses rapidly before swallowing. The aim of this study is to compare the readymade exciepient blend designed for orodispersible tablets with the conventional method to manufacture them using levofloxacin as the active pharmaceutical ingredients. Different formulas were prepared to compare the powder characteristics and then were compressed using direct compression method. The compressed tablets were then evaluated for their physical characteristics and drug release properties. Results showed that using the readymade blend was advantageous regarding powder and tablets physical properties as well as drug release and dissolution.
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