Biography
I have completed my Master course at the age of 25 in Food Microbiology from Gorgan University. I have worked on probiotic bacteria a smy thesis and have 4 under submision papers in this fuild. I also was as co-worker in a PhD thesis under the title of “Molecular identification of lactic acid bacteria isolated from dairy products and study of their anti-cancer properties†under supervision of Dr. Khomeiri, associate professor in University of Gorgan.
Abstract
Cancer is ranked as the deadliest disease worldwide after cardiovascular disease. Tens millions cases annually are diagnosed to cancer around the world and among them colorectal cancer is the third leading cause of cancer mortality. There are several epidemiological evidences supporting a protective role of probiotic bacteria as biotherapeutics against cancer, especially colon cancer. In vivo and In vitro studies demonstrated that intracellular and extracellular probioactive metabolites of probiotics such as enzymes, peptides, organic acids and especially short fatty acids produced through fermentative activities of probiotics in the gut show anti-tumorigenic attributes. Lactic Acid Bacteria (LAB) as the most common types of probiotics are an ecologically divers group of bacteria united by producing lactic acid as fermentation product play a major role in treatment and prevention of a variety of disease like as cancer. Furthermore, it has also been reported that ingredients of decomposed probiotic dead bodies have preventive and therapeutic impacts on cancer when they die and leave epithelial texture of the host’s colon. This study summarizes the latest identified anti-tumor pharmabiotics from different species of probiotic bacteria with focus on LAB.